Complementary & Alternative Medicine – Chemistry & Standards
Complementary & Alternative Medicine – Chemistry & Standards
The R&D team focuses on TCM authentication, TCM product QA/QC, new TCM product development, and helps in the development of local ISO standards with Singapore’s TCM technical committee.
Our capabilities include TCM product safety and efficacy (in vivo and in vitro testing) and chemical fingerprinting (HPLC, LC-MS/MS, GC/MS, FTIR).
Our industry partners include Eu Yang Sang International, Singapore College of TCM, Singapore Chinese Druggists Association, Yi Shi Yuan, and The Medicine Manufacturing Association of Singapore.
Industry Partners
Iconic Project : Safer Red Yeast Rice Nutritional Supplement
Red Yeast Rice (RYR) is produced by fermenting cooked non-glutinous whole rice kernels with the yeast, Monascus purpureus. RYR has been used by the Chinese since 800 A.D. as fermented food and medicine to stimulate blood circulation and digestion.
With the discovery that RYR produces a chemical called monacolin K, which inhibits the body’s production of cholesterol, it has been developed as a popular functional supplement for reducing cholesterol.
Our team seeks to develop a simple and rapid method to remove the majority of water-soluble compounds present in RYR. The new RYR should be safer for patients with multi-cardiovascular diseases as water-soluble RYR extracts causing potential herb-drug interaction(s) to have been removed.
A patent filed over 10 different countries (including US, China, Canada, Japan…etc) on the proprietary processing method and potential novel applications of the water-soluble RYR.
The product has been marketed under Eu Yang Sang International, Singapore since 2012 until now.
The current method for authentication of Edible Bird’s Nest (EBN) is based on physical appearance and requires a skilled grader to distinguish genuine from fake samples.
The life sciences team developed a method of authenticating EBN with hyperspectral imaging. This novel method has not been reported in any scientific journal. It was granted a Singapore Patent in 2018.
The team further improvised to use Near Infra-red Spectroscopy (NIRS) for EBN grading. This method is more accurate, faster, and very easy to use.